Technology

Resipher is a long term, non-invasive oxygen consumption rate (OCR) monitoring system that works 24/7 inside your incubator.
OCR measures the rate of mitochondrial respiration that provides insight into important cellular processes:
  • – Metabolic activity
  • – Cell proliferation
  • – Drug effects
  • – Mitochondrial function
Resipher is the only seamless and fully integrated 96-well plate cell culture workflow system.
Our groundbreaking platform utilizes patented miniature ultra-sensitive oxygen probes paired with a novel algorithm which continuously characterizes the vertical oxygen gradient that naturally forms above cells as they consume oxygen. This innovative design ensures that cells remain undisturbed while continuously monitoring each individual well within your chosen 96-well microplate, capturing precise measurements of oxygen gradients continuously.
At Lucid Scientific, we understand the importance of efficiency and reproducibility in scientific research. That’s why our innovative approach not only provides unique insight into dynamic changes in cellular metabolism, but the setup and usage is radically simple. With superior robustness, reliability, reproducibility, and scalability, our platform empowers scientists to delve deeper into metabolic processes with confidence.
Experience the future of research firsthand – try our flagship product, the Resipher, and unlock new possibilities for advancement in your field. What’s more, our noninvasive methodology ensures that cells remain undisturbed throughout the measurement process. This opens the door for seamless integration with a myriad of complementary techniques, including multiomics, imaging, impedance, fluorescent-based assays, and beyond. By pinpointing metabolic shifts in real-time, researchers can execute a diverse range of scientific approaches precisely when they’re needed most.

Products

Resipher

Resipher magnetically attaches to our single-use sensing lids that rest securely on most standard 96-well plates.

Sensor

Optical sensors measure oxygen concentrations through openings on the underside of Resipher.

Lids

Individually sterilized single-use sensing lids attach between the Resipher and the well plate.

Hub

Up to 8 devices are connected to a hub that stores all data locally and pushes to the cloud. LEDs indicate status while devices are in the incubator.

Technical Specification

Lucid Lab

Our cross-platform web application allows your team to create and manage experiments, stream and monitor data from devices in real-time, and generate plots that are ready for publishing.

Comprehensive plots

Detailed O2 analysis

Curate and present the most important data with advanced plotting capabilities. Plots update in real-time for live experiments.
High resolution gradient data is presented for all wells comparing response against time and height of Resipher at the time of reading.

Reactive controls

Plate maps, well conditions and plots are interactive and visually connect to help quickly identify correlations and trends.

Adaptable tools

Flexible plate labelling and well mapping tools accommodate all types of experimental conditions.